It's really difficult to answer in a good way.
In general i use ADS and/or AppCAD to calculate and simulate the traces.
For your kind of antenna i think it's enough to respect the "basic RF rules" so:
Maintain the characteristic impedance of the system, tipically 50 ohm
Use the correct lenght in order to achieve the best resonance performance, tipically lambda/2
Do not place any other kind of component under, near and "in front of" the RF traces and antenna
Prefer 0402 or 0603 instead bigger size for matching
Choose the best antenna solution and shape for better performance in sensitivity and try to layout it without any compromise around RF traces
I've reat the nRF52832 datasheet very easily and my opinion is to use at least 4 layer PCB, less distance between GND plane and RF traces gives better performance.
If you can't work with 4 layers use 2 layers but with PCB thickness around 1mm at least
This is some good materials about RF design:
Helpful tips for finding updated Semtech product documentation.
It's really generic but i hope this can help in your design
It's so difficult to explain a "difficult" and huge argument like RF in this way